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G O Gbotosho Selected Research

Pyrimethamine (Daraprim)

2/2007The effects of artemether-lumefantrine vs amodiaquine-sulfalene-pyrimethamine on the hepatomegaly associated with Plasmodium falciparum malaria in children.
12/2006Effects of pyrimethamine-sulphadoxine, chloroquine plus chlorpheniramine, and amodiaquine plus pyrimethamine-sulphadoxine on gametocytes during and after treatment of acute, uncomplicated malaria in children.
4/2006Predictors of the failure of treatment with pyrimethamine-sulfadoxine in children with uncomplicated falciparum malaria.
11/2005Open randomized study of artesunate-amodiaquine vs. chloroquine-pyrimethamine-sulfadoxine for the treatment of uncomplicated Plasmodium falciparum malaria in Nigerian children.
7/2005Effects of antifolates--co-trimoxazole and pyrimethamine-sulfadoxine--on gametocytes in children with acute, symptomatic, uncomplicated, Plasmodium falciparum malaria.
5/2004Open randomized study of pyrimethamine-sulphadoxine vs. pyrimethamine-sulphadoxine plus probenecid for the treatment of uncomplicated Plasmodium falciparum malaria in children.

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G O Gbotosho Research Topics

Disease

15Malaria
01/2016 - 07/2003
13Falciparum Malaria (Plasmodium falciparum Malaria)
03/2009 - 03/2004
9Infections
01/2016 - 07/2003
2Body Weight (Weight, Body)
05/2015 - 11/2005
2Fever (Fevers)
05/2004 - 04/2003
1Neoplasms (Cancer)
01/2014
1Hepatomegaly
02/2007
1Pneumonia (Pneumonitis)
04/2006
1Parasitemia
10/2005
1Acute malaria
07/2005

Drug/Important Bio-Agent (IBA)

10Chloroquine (Aralen)FDA LinkGeneric
01/2008 - 07/2003
9Antimalarials (Antimalarial Agents)IBA
01/2016 - 05/2004
6Pyrimethamine (Daraprim)FDA Link
02/2007 - 05/2004
5Pharmaceutical PreparationsIBA
01/2016 - 09/2005
5Amodiaquine (Camoquin)FDA Link
05/2015 - 11/2005
3artemisinin (artemisinine)IBA
05/2015 - 11/2005
3Chlorpheniramine (Chlorphenamine)FDA LinkGeneric
01/2008 - 06/2005
3Sulfadoxine (Sulformethoxine)FDA Link
04/2006 - 07/2005
2ArtesunateIBA
12/2011 - 11/2005
2Lumefantrine Drug Combination Artemether (Coartem)FDA Link
03/2009 - 02/2007
2Codon (Codons)IBA
03/2009 - 12/2006
2Promethazine (Promet)FDA LinkGeneric
01/2008 - 03/2004
2Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric
04/2006 - 07/2005
2Merozoite Surface Protein 1 (MSA1)IBA
01/2004 - 07/2003
1PhytochemicalsIBA
01/2016
1Anti-Bacterial Agents (Antibiotics)IBA
05/2015
1Ciprofloxacin (Cipro)FDA LinkGeneric
05/2015
1Adenosine Triphosphatases (ATPase)IBA
03/2009
1LumefantrineFDA Link
01/2009
1Sulfalene (Longum)IBA
02/2007
1Histamine H1 Receptors (Histamine H1 Receptor)IBA
12/2006
1Membrane Proteins (Integral Membrane Proteins)IBA
07/2006
1Drug CombinationsIBA
04/2006
1pyrimethamine drug combination fanasil (Fansidar)FDA Link
09/2005
1Tetrahydrofolate Dehydrogenase (Dihydrofolate Reductase)IBA
09/2005
1Dihydropteroate Synthase (Dihydropteroate Synthetase)IBA
09/2005
1Folic Acid AntagonistsIBA
07/2005
1Probenecid (Benemid)FDA LinkGeneric
05/2004
1Histidine (L-Histidine)FDA Link
03/2004
1Proteins (Proteins, Gene)FDA Link
03/2004
1Soaps (Soap)IBA
04/2003

Therapy/Procedure

5Therapeutics
05/2015 - 04/2006
2Aftercare (After-Treatment)
03/2009 - 12/2006
1Duration of Therapy
01/2009